Friday, April 3, 2015

The Jeffrey Epstein VI Foundation Funds Study that Identifies How Tumors Grow

NEW YORK, / Mathematic studies at the Program for Evolutionary Dynamics (PED) at Harvard University, and funded by the Jeffrey Epstein VI Foundation, have shown that the most aggressive cells within tumors can be visually identified for elimination. These aggressive cells are the driver mutations that drive the tumor's growth. The study, which shows a topological map of what to look for when examining tumors, comes at a needed time in cancer research, for while tumor cells can be extracted from biopsy, it's very difficult to know which cells are actually causing the growth. And for inhibitor drugs to work, they have to target the most genetically aggressive cancer cells, amongst others.

The Program, or PED, studies the evolution of living systems with the use of mathematics. Much of their work focuses on the evolution of cancer and has significantly impacted treatment at universities across the country. Funding their work is an inscrutable New York private fund manager, called Jeffrey Epstein. Epstein established the PED in 2003 with a $30 million dollar gift to the university and his science foundation is one of the largest donors to individual scientists around the world including a list of luminaries such as Stephen Hawking and Nobel laureates, Gerard 't Hooft, David Gross and Frank Wilczek.

One of the great challenges of cancer is that tumors are genetically diverse, making it extremely difficult to tackle them with tailored inhibitor drugs. In 2010, the PED showed that even small solid tumors contain at least 40 to 100 genetic mutations within its structure, and that only 5 to 15 of those actually drive tumor growth. The findings highlighted the urgency for better genetic profiling of tumor masses beyond random excision, and the need to pinpoint the minority of tumor cell aggressors.

The PED's spatial modeling of how tumors grow however, now offers the first mathematically proven map of how to visually target the key aggressors within a tumor.

"Mathematics in medical research reveals patterns that are otherwise hidden and it's exhilarating when a mathematician can determine cellular behavior with the precision of an engineer," Jeffrey Epstein asserted.

The Jeffrey Epstein VI Foundation Backs the Largest Science Fair in the USVI

The Jeffrey Epstein VI Foundation, under the umbrella of the Southern Trust Company, Inc. has funded the largest and most important student science fair in the US Virgin Islands. The fair, called the St. Thomas-St. John STEM Fair, was spearheaded by the Virgin Islands Department of Education and consisted of hundreds of grade school students from across the islands, to showcase their science projects for awards at the University of the Virgin Islands Sports and Fitness Center.

STEM stands for Science, Math, Engineering and Technology, and has become a known acronym for a rigorous science curriculum in schools. The Jeffrey Epstein VI Foundation, was founded by St. Thomas resident, Jeffrey Epstein, who plays an active role in supporting science education across the US Virgin Islands. The foundation is also known for establishing the graduate Program for Evolutionary Dynamics at Harvard.

At the fair, the foundation supplied more than a hundred Microsoft Surface 2 computers, Touch keyboards and Nylon Sleeves for the Microsoft Surface. The foundation also provided funds to host the fair, travel and accommodation funding for the winners and their chaperones and accommodation support for the STEM summer camps.

“The STEM fairs provide an exciting and important incentive for students across the Virgin Islands to participate in science projects at school and at home,” Jeffrey Epstein remarked.

The STEM fair oversaw more than 165 projects; and the caliber was astounding. One 11 year old prize winner, Ricky James Jr. for example, showed how to power a calculator with a just a penny instead of batteries. Other projects included a solar powered speed boat and a juicer made from a garbage door motor and recycled dishwasher parts.

The top scorers in each category were presented with a STEM trophy, a plaque, a STEM certificate and an iPad. Science categories ranged from research, science demonstrations, math real world problem investigations, math real world models, video presentation, Powerpoint presentations, music technology, Web page design, desktop publishing and programming.

In addition to its work in the US Virgin Islands, the Jeffrey Epstein VI Foundation supports cutting edge science research across the United States and for establishing the Program of Evolutionary Dynamics at Harvard University in 2003.

Jeffrey Epstein VI Foundation Funds Research to Prevent Crohns and Colitis Disease

NEW YORK, March 12, 2014 /PRNewswire/ -- Crohns and Colitis Disease is a chronic disease of the lower intestinal track, causing inflammation and a host of crippling symptoms from ulcers to intestinal rupture. The disease affects approximately 700,000 Americans and many more suffer from undiagnosed irritable bowel syndrome. To date, not much is known about the ultimate cause of Crohns but for the first time in its history researchers are targeting the bacteria that cause the inflammation.

Founded by the science and Harvard philanthropist, Jeffrey Epstein, the Jeffrey Epstein VI Foundation has been an avid supporter of the Crohns and Colitis Foundation of America's (CCFA) initiative to identify the bacteria that cause bowel inflammation. Specifically, the CCFA backs pivotal research called the Microbiome Initiative—which identifies 14 bacterial metabolic profiles associated with IBD.

To tackle these 14 bacteria types, researchers are developing the first line of inhibitors to block specific bacterial metabolic pathways, along with dietary supplements to redirect bacterial metabolites.

"This is the first time that a treatment for Crohns and Colitis addresses the cause, instead of the symptoms," Jeffrey Epstein remarked. "Even though we don't know the root cause of the disease, except for a possible genetic disposition, drugs will soon block the bacteria that cause inflammation."
"We anticipate that in the next three to five years, we will have isolated microbial targets and develop strategies that will form the basis for new therapeutic interventions," Dr. R.Balfour Sator stated, who is CCFA Chief Medical Advisor and Midget Distinguished Professor of Medicine, Microbiology & Immunology, and Director of the UNC Multidisciplinary IBD Center.

The Jeffrey Epstein VI Foundation also supports the CCFA's Genetics Initiative which focuses on the more than 100 internationally-identified genetic factors that contribute to IBD risk. To date, seven high-priority genetic pathways that regulate immune function or the intestinal lining cell response to injury have been targeted for intensive investigation for inhibitor therapy.

Jeffrey Epstein is the founder of the Program for Evolutionary Dynamics at Harvard University. He is also a former board member of the Mind, Brain and Behavior Committee at Harvard and a former board member of Rockefeller University.


Friday, November 21, 2014

NeuroTV: Jeffrey Epstein Helps Bring Brain Science to the Public


A Harvard Financier, Jeffrey Epstein, Helps Bring Brain Science to the Public

The Jeffrey Epstein VI Foundation helps launch NeuroTV, a highly popular academic program on the brain.

NEW YORK, Nov. 11, 2014 / -- One of the hottest areas on the Internet is not gaming or sports, but academic content, especially in the sciences. In fact, subscribers to educational YouTube channels tripled in 2013, with popular science topics leading the pack. Producers like AsapScience, or TED can get millions of viewers over months. Missing on TV and online however, is in-depth academic content, especially in the sciences, despite booming viewership for the small number of brainiac programs.

Now an unusual Harvard investor and private financier, called Jeffrey Epstein, has helped fund NeuroTV, the largest online network devoted to academic interviews on everything neuroscience. NeuroTV's guest speakers are not run of the mill professors: two recent guests, May-Britt and Edvard Moser, directors of the Kavli Institute for Systems Neuroscience, were awarded the 2014 Nobel Prize in Medicine for the discovery of grid cells. Other guests include: Hank Greely, Director of the Center for Law and the Biosciences and Professor of Genetics, at the Stanford School of Medicine and Sebastian Seung Professor of Computational Neuroscience at MIT.

"NeuroTV provides in-depth interview models, that delves deeply into science topics," Jeffrey Epstein asserted whose foundation, the Jeffrey Epstein VI Foundation, established the graduate Program for Evolutionary Dynamics at Harvard University in 2003 with a $30 million dollar gift. "The episodes don't tone down academic language, but provide video content that can be used in classrooms around the world, as well as a platform to educate and inspire."

In addition to establishing the Program for Evolutionary Dynamics, which studies the mathematics of evolution with a focus on diseases, Epstein was a former board member of Harvard's Mind, Brain and Behavior Committee and has funded numerous brain research initiatives at the university. Epstein's affinity for promoting public access to academic science however, probably stems from his own self-taught background and the belief that higher education should be widely available.

To date, NeuroTV has launched 13 episodes with another 13 planned for Season 2. Viewership is rapidly growing with episodes typically gathering thousands of viewers within the first six months.